IISO flange enkuluumgangatho waziwa ngokuba LF, LFB, MF okanye ngamanye amaxesha nje ISO flange. Njengakwi-KF-flanges, iiflange zidityaniswe ngumsesane ophakathi kunye ne-elastomeric o-ring. Isibambiso esongezelelweyo sesetyhula esilayishwe entwasahlobo sihlala sisetyenziselwa ukujikeleza amakhonkco o-o-diameter amakhulu ukuwathintela ukuba angaqengqeleki ukusuka kumsesane ophakathi ngexesha lokunyuswa.

Iiflange ezinkulu ze-ISO ziza kwiindidi ezimbini. Iiflange ze-ISO-K (okanye i-ISO LF) zidityaniswe nezibambene ezinezizipho eziphindwe kabini, ezithi zibambelele kumjelo ojikelezayo kwicala letyhubhu leflange. Iiflange ze-ISO-F (okanye i-ISO LFB) zinemingxuma yokudibanisa iiflange ezimbini ngeebholiti. Iityhubhu ezimbini ezine-ISO-K kunye ne-ISO-F flanges zinokudityaniswa kunye ngokucinezela icala le-ISO-K ngeeclamp ezine-claw enye, ezithi zibotshelelwe kwimingxuma ekwicala le-ISO-F.

Iiflange ezinkulu ze-ISO zifumaneka ngobukhulu ukusuka kwi-63 ukuya kwi-500 mm ubukhulu betyhubhu yegama.